Why PRECIFER Works Better
Standard iron salts (like Ferric ammonium citrate, Iron Polymaltose, Ferrous Sulfate etc) often lead to poor compliance because only 10–15% is absorbed, leaving the rest to irritate the gut, cause black stools, and feed “bad” bacteria.
The PRECIFER Difference:
- Microencapsulation: Nanosized iron particles are coated in a protective layer, preventing contact with the stomach lining.
- Targeted Release: Iron is released specifically in the duodenum (small intestine) where absorption is highest.
- Lactoferrin Synergy: Lactoferrin acts as a smart carrier, “pulling” iron into the bloodstream more efficiently than iron alone.
- Taste Masked: No unpleasant metallic aftertaste.
- Can be consumed any time without worry of other minerals interaction.
Key Benefits
✔ Rapid Hemoglobin Recovery: Ideal for treating Iron Deficiency Anemia (IDA).
✔ Boosts Energy & Focus: Reduces fatigue and “brain fog” associated with low iron.
✔ Gut-Friendly Formula: Safe for those with sensitive stomachs or IBS.
✔ Healthy Pregnancy: Supports maternal health and fetal development without the usual nausea.
✔ Other common iron deficiency anemia -women, and elderly.
Who Should Use It
- Individuals with Iron Deficiency Anemia (IDA) expecting quick hemoglobin increase.
- Pregnant and lactating women.
- Athletes and active individuals experiencing “Sports Anemia.”
- Elderly patients with malabsorption issues.
- Those who suffer from constipation or nausea with standard iron tablets.
Comparison: PRECIFER vs. Standard Iron
| Feature | Regular Iron Salts | PRECIFER Capsules |
| Absorption | Low (10-15%) | High (3x More) |
| Stomach Upset | Frequent (Nausea/Cramps) | Virtually Zero |
| Constipation | Very Common | Unlikely |
| Metallic Taste | Strong/Unpleasant | None |
| Clinical Response | Slow (Months) | Fast Visible Results |
Recommended Dosage
- 1 capsule daily after a meal, or as directed by a healthcare professional.
Frequently Asked Questions (FAQ)
- What makes PRECIFER -Liposomal Iron and Liposomal Lactoferrin different from other iron capsules? It uses microencapsulated iron and Lactoferrin, which ensure the iron reaches your blood rather than sitting in your gut causing irritation.
- Does PRECIFER cause constipation? No. Because the iron is encapsulated and highly absorbed, there is very little “unabsorbed” iron left to cause constipation.
- Why is Lactoferrin included? Lactoferrin is a protein that naturally binds to iron and helps transport it across the intestinal wall, significantly boosting effectiveness.
- Can I take this during pregnancy? Yes, PRECIFER is excellent for pregnancy as it is gentle on the stomach and effectively supports both mother and baby. However, consult your doctor.
- Will it turn my stools black? While some darkening can occur, it is significantly less than with traditional iron salts due to better absorption.
- How soon will I see results in my Hemoglobin levels? Most users see a noticeable improvement in energy within 2 -3 weeks and clinical Hb increases within 30 days.
- Does it have a metallic taste? No, the microencapsulation masks the metallic taste completely.
- Can I take it on an empty stomach? While it is gentler, we recommend taking it after a meal for optimal nutrient synergy with the co-vitamins.
- Is it safe for long-term use? Yes, it is designed for safe maintenance of iron stores, but always consult your doctor for long-term needs.
- Do i have to Vitamin C separately? No, with Liposomal Iron and Liposomal lactoferrin, additional absorption enhancer like Vitamin C is not necessary. At the same time, taking orange juices along or during the time with anemia will provide an additional benefit.
- Is it suitable for vegetarians? The Lactoferrin is milk-derived, making it suitable for lacto-vegetarians.
- Can children take PRECIFER? It is suitable for older children (8+) who can safely swallow capsules. Consult a pediatrician for younger children.
- Will it stain my teeth? No. Unlike liquid iron or some tablets, the encapsulated form prevents contact with teeth.
- How does it help with immunity? Lactoferrin is a key part of the innate immune system, helping to deprive harmful bacteria of iron while supporting your own cells.
- Can I take it with my morning tea? Although liposomal iron is less likely to interfere with tea or other minerals, it is still advisable to maintain a gap of at least one hour before taking PRECIFER for optimal absorption.
Evidence
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Latest Scientific Studies on Encapsulated Ferric Pyrophosphate Iron
Efficacy and Safety of Microsomal Ferric Pyrophosphate Supplement for Iron Deficiency Anemia in Pregnancy; Cureus 2024
Key Findings
These findings suggest that Encapsulated Ferric pyrophosphate could be a valuable therapeutic option for managing iron deficiency anemia in pregnant women, promoting better maternal and fetal outcomes. Further research with an increased sample size is warranted to delve into the underlying mechanisms behind these positive outcomes, nonetheless, our study provides a promising foundation for addressing this critical health issue.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11056223/
Effects of micronised microencapsulated ferric pyrophosphate supplementation in patients with advanced cancer and iron deficiency: a single-centre cohort pilot study; Jr of Blood Transfusion 2021
Key Findings
The supplementation of 30 mg/d of micronized Ferric pyrophosphate in combination with 80 mg/d of ascorbic acid in advanced cancer patients with hyposideraemia led to a significant increase in sideraemia and ferritinaemia. Moreover, in some of the patients whose serum iron level did not increase, an increase in haemoglobin was observed.
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6596375/
Efficacy of a Novel Food Supplement (Ferfer®) Containing Microencap in Liposomal Form in Female Iron Deficiency Anemia ; Cureus 2019
Key Findings
Treatment of IDA with microencapsulated liposomal iron pyrophosphate sachets significantly increases serum hemoglobin levels in non-pregnant women of reproductive age.
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Micronized, Microencapsulated Ferric Iron Supplementation in the Form of >Your< Iron Syrup Improves Hemoglobin and Ferritin Levels in Iron-Deficient Children: Double-Blind, Randomized Clinical Study of Efficacy and Safety; Jr Nutrients 2021
Key Findings
A 12-week supplementation with microencapsulated Iron Syrup resulted in a significant increase in ferritin and hemoglobin levels as compared to placebo (p = 0.04 and p = 0.02). Adverse events were reported with similar frequencies across both study arms. Ferric pyrophosphate microencapsulated represents an effective, well-tolerated, and safe option for the management of nutritional iron deficiency in children.
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https://www.mdpi.com/2072-6643/13/4/1087
Liposomal Iron for Iron Deficiency Anemia in Women of Reproductive Age: Review of Current Evidence; Jr of OB & Gynecology 2018
Key Findings
Encapsulation of micronized iron in liposomes is associated with lesser exposure to gastric contents, lesser interaction with food contents, no exposure to different digestive juices, targeted delivery of iron and allows lower doses to be administered in lieu of direct absorption without need for protein carriers. The available evidence suggests that liposomal iron significantly increases hemoglobin, ferritin levels in pregnant women as well as in women with iron deficiency.
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https://www.scirp.org/journal/paperinformation?paperid=87213
A Novel Approach for Iron Deficiency Anaemia with Liposomal Iron: Concept to Clinic; Jr of OB & G 2020
Key Findings
Conventional oral iron therapy is limited in many patients because of dose dependent side effects, insufficient absorption, lack of compliance and limitation in various inflammatory conditions. Liposomal iron is a technologically designed, innovative form of iron which due to its differential delivery system ensures higher absorption and bioavailability, greater tolerability and least gastro-intestinal side effects unlike conventional oral iron preparations. This review provides a critical discussion and a comprehensive view based on the author’s review of the medical literature concerning the technology of liposomal iron preparation, mechanism of its absorption, its advantage over conventional iron preparations and clinical evidence on its usage in iron deficient states in pregnancy and certain inflammatory conditions.
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https://www.scirp.org/journal/paperinformation?paperid=87213
Efficacy of a microencapsulated iron pyrophosphate-fortified fruit juice: A randomised, double-blind, placebo-controlled study in Spanish iron-deficient women; Br Jr of Nutrition 2011
Key Findings
The fruit juice consumption involved increased intake of carbohydrates and vitamin C, and increased BMI within normal limits. Ferritin was higher in the F group after week 4 (P < 0·05) and became 80 % higher than in the P group after week 16 (P < 0·001), and transferrin decreased in the F group compared with the P group after week 4 (P < 0·001). RDW was higher at weeks 4 and 8 in the F group compared with the P group (P < 0·05). Transferrin saturation increased after week 8, and haematocrit, MCV and Hb increased after week 12, in the F group compared with the P group. Serum Fe did not change. sTfR and ZnPP decreased in the F group at week 16 (P < 0·05). Iron pyrophosphate-fortified fruit juice improves Fe status and may be used to prevent Fe-deficiency anaemia.
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Oral Liposomal Iron: A Treatment Proposal for Anemia; World Jr of Anemia 2017
Key Findings
The prevalence of any type of anemia is very high (>95%) among children, adolescents, and pregnant women in India. The main risk factors for iron deficiency anemia (IDA) are: Low iron intake, different levels of chronic blood loss, and malabsorption. In addition, certain chronic diseases like chronic kidney disease (CKD), chronic heart failure, cancer, and inflammatory bowel disease (IBD) are frequently associated with IDA.2,4 Iron deficiency anemia is also known to affect a large part of adult and elderly patients in internal medicine units. The distinctive features of liposomal iron like high bioavailability, lesser side effects, and good compliance make it suitable to be used in patients who require iron administration and are intolerant to oral treatment, IV iron treatment, or lack good absorption.
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https://www.wjoanemia.com/doi/WJOA/pdf/10.5005/jp-journals-10065-0019
Oral Ferric Pyrophosphate Formulation Utilization Surveillance Study to Assess Clinical Impact on Hemoglobin levels: Maxiim-Hemoglobin Study; Int jr of scientific study 2019
Key Findings
A total of 60 gynecologists participated and completed the survey, which involved 1073 pregnant subjects and patients suffering from IDA (864 patients, i.e., 80%). Mean Hb level at baseline was found to be 8.98 g/dl, 10.03 at week 4, and 10.99 at week 8. Thus, rise of Hb from baseline to week 8 was found to be 2.01 g/dl. Adverse events were reported in only 10 patients. The study suggests that oral Ferric pyrophosphate formulation therapy can serve as potent choice of therapy for IDA in pregnancy, both therapeutically and prophylactically.
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https://www.ijss-sn.com/uploads/2/0/1/5/20153321/10_ijss_jan_oa10_-_2019.pdf
Tarangani –
No gastritis, unlike other iron brands like ferium, c-pink and veg capsule makes it more suitable. Precifer i recommend
Dr.Rajagopal –
I am naturopathy practitioner and first time i am seeing encapsulated iron with lactoferrin addition, which i consider as the most logical way to boost low Hb count. Good results and no side effects; am happy with Precifer
sandeep arora –
Precifer -product and packing looks good and i hope it should be working to normalize my hemoglobin.
linda thomas –
i was using an imported ferric iron and it was expensive. Now i am getting same benefits with Precifer; happy to use and recommend.
Roja –
For my anemia related to pregnancy when the doctor prescribed some regular iron and it was causing severe gastritis. same time i came to know about Precifer thru a friend and my doctor also allowed to shift to precifer. Result is good, no gastritis and my hb level improved with 4 weeks.